Blockchain in Healthcare Today https://blockchainhealthcaretoday.com/index.php/journal <p><strong>Blockchain in Healthcare Today (BHTY)</strong> is the leading international open access peer reviewed journal that amplifies and disseminates platform approaches in healthcare and distributed ledger technology research and innovations. Fields of interest include healthcare information systems, leveraging data science tools and techniques, interoperability, consent mechanisms, privacy preservation, security of health data, clinical trials management, supply chain management, revenue cycle automation, immersive technologies, tokenomics, governance, regulation, network technologies, clinical computing, cryptography, and failed experiments in this evolving specialty field of research.</p> <p>Founded in 2018, the historic journal is credited with creating and validating this new technology and research field, bridging research excellence with real world market implementations and impact. A world class peer review board offers constructive commentary to strengthen work.</p> Partners in Digital Health, 241 Hamilton Avenue, Suite 21 Stamford, CT 06902, USA en-US Blockchain in Healthcare Today 2573-8240 <p><span style="color: #4b7d92;">Auth</span><span style="color: #4b7d92;">ors retain copyright of their work, with first publication rights granted to Blockchain in Healthcare Today (BHTY). Read the full <a href="https://blockchainhealthcaretoday.com/index.php/journal/copyright">Copyright Statement</a>.</span></p> <p> </p> <p> </p> Accelerating the Worldwide Adoption of Blockchain Technology https://blockchainhealthcaretoday.com/index.php/journal/article/view/278 <p><em>“To understand innovation you should ask "why not?" and not "why?" Selling (blockchain) is a problem and people and companies are blocking adoption which prevents innovation within a company, and stymies costs savings and&nbsp; efficientcy - that is the problem.&nbsp; It's a problem to be stuck in an innovation department - blockchain needs to be used in operations. Scientists and technologists need to understand one another better to create opportunity and success" - Raja Sharif, CEO, ATMPS</em></p> <p>In 2022, the team at ATMPS&nbsp; launched a potential game changer with a new approach to cell and gene therapy tracking, allowing more streamlined applications, payment options, and opportunity to realize true manufacturing safety and trust at scale, faster for personalized medicines and regimen treatments. The speaker highlights his experiences, and overcomes market challenges empasizing the need for better commercialization strategies for blockchain. In addition, the fllowing topics are addressed in the keynote:</p> <ul> <li>Automated Processes</li> <li>Regulatory Visibility &amp; Compliance, FDA 21 CFR , HIPAA, GDPR</li> <li>Putting Together Blockchain&nbsp;Architecture for IRTS &amp; ERH Integration</li> <li>Patient Apps and Mobile Device Issues</li> <li>Supply Chain</li> </ul> Raja Sharif Copyright (c) 2023 Raja Sharif http://creativecommons.org/licenses/by-nc/4.0 2023-08-18 2023-08-18 6 2 10.30953/bhty.v6.278 Highlights from Advancing the Business of Health with Blockchain and Frontier Tech at ConV2X Symposium 2023 https://blockchainhealthcaretoday.com/index.php/journal/article/view/288 Tory Cenaj Copyright (c) 2023 Tory Cenaj http://creativecommons.org/licenses/by-nc/4.0 2023-11-21 2023-11-21 6 2 10.30953/bhty.v6.288 Innovative Minds Shine Bright at the 2023 ConV2X Pitch Competition https://blockchainhealthcaretoday.com/index.php/journal/article/view/283 <p>On Sept 1, 2023, Partners in Digital Health, publisher of Blockchain in Healthcare Today (BHTY,) conducted the 4th Annual ConVerge2Xcelerate (ConV2X) Ignition Pitch Competition. The competition was recorded for journal and On Demand broadcast viewing. Seven competitors in the digital health and DLT markets presented to eight decerning judges. Entrants were asked to demonstrate how products and services directly impact the telehealth and blockchain in healthcare technology fields from around the globe. Product solution catgories included, but were not limited to:</p> <p><strong>AI &amp; Tech in Telehealth and Medicine</strong></p> <ul> <li>Smart home care design, AI, sensors, robotics, chronic care condition(s) using RPM, reducing cost for health systems or patients, enhancing the physician-patient relationship, mixed reality to enhance outcomes in patient care, etc.</li> </ul> <p><strong>Advancing the Business of Health with Blockchain Technology</strong></p> <ul> <li>Monetization of data, interoperability, improving population health, precision medicine, public health &amp; equity, digital twins, secure identity, DeFi, medical metaverse, supply chain, clinical trials, etc.</li> </ul> <p>Scores were rated from 1-5, with 5 being the highest/best. Criteria appears below. Scores were taillied, and winners selected for each category.</p> <div> <blockquote> <ul> <li><strong>Impact:</strong></li> <ul> <li>How likely is the solution to improve outcomes for the problem identified?</li> </ul> <li><strong>Innovation:</strong></li> <ul> <li>Does the team provide a convincing rationale for why their solution may work?</li> <li>Does the solution provide a creative approach and address specific user needs?</li> </ul> <li><strong>Scalability:</strong></li> <ul> <li>How easy would it be to develop and implement this solution?</li> <li>Could this solution scale across different markets and therapeutic areas?</li> </ul> <li><strong>Presentation:</strong></li> <ul> <li>How effective was the presentation overall?</li> <li>Was the solution they are proposing convincingly articulated, presented or visualized?</li> </ul> </ul> </blockquote> </div> Tory Cenaj Copyright (c) 2023 Tory Cenaj http://creativecommons.org/licenses/by-nc/4.0 2023-11-03 2023-11-03 6 2 Blockchain Technology Predictions 2024: Transformations in Healthcare, Patient Identity and Public Health https://blockchainhealthcaretoday.com/index.php/journal/article/view/287 <p>In an era characterized by the convergence of cutting-edge technologies, the world of healthcare and public health is on the brink of a profound transformation that will shape the future of medicine and wellness. This transformation is not merely an incremental step forward; it is a paradigm shift. It is driven by the synergistic integration of digital twins, blockchain technology, artificial intelligence (AI), and multi-omics platforms, collectively propelling us into uncharted territory. The integration of these innovations holds the potential to rewrite the rules of engagement in clinical trials, revamp the strategies for preventing public health crises, and redefine the way we manage, share, and secure healthcare data. As we embark on this journey of exploration and innovation, we find ourselves at a pivotal juncture, akin to the invention of the microscope in biology or the discovery of antibiotics in medicine. We are at the crossroads of a new era, one that teems with immense promise and transformative power.&nbsp;</p> Gianluca De Novi, PhD Natalia Sofia, PharmD, Msc Ingrid Vasiliu-Feltes MD EMBA Christine, Yan Zang, PhD Frank Ricotta Copyright (c) 2023 Gianluca De Novi, PhD , Natalia Sofia, PharmD, Msc , Ingrid Vasiliu-Feltes MD EMBA, Christine, Yan Zang, PhD, Frank Ricotta http://creativecommons.org/licenses/by-nc/4.0 2023-11-21 2023-11-21 6 2 10.30953/bhty.v6.287 Problems with Medical Claims that Artificial Intelligence (AI) and Blockchain Can Fix https://blockchainhealthcaretoday.com/index.php/journal/article/view/273 <p>In medical insurance, there are both valid and legitimate claims that should be covered by the insurer and fraudulent or inappropriate claims that should not be paid. Problems arise in scenarios when valid claims are not paid and when fraudulent or inappropriate claims are paid. Hospitals and insurers play critical roles in these cases. Artificial Intelligence (AI) and blockchain technologies can play significant roles in addressing the problems associated with medical insurance claims. Some of the ways in which these technologies can help are using AI algorithms to analyze data stored on the blockchain for fraud detection, and leveraging blockchain's transparency to improve the accuracy of AI models by providing access to a larger dataset. The author addresses approaches for each senario.</p> Joe Hawayek Osama AbouElKhir, MD Copyright (c) 2023 Joe Hawayek, Osama Aboulkheir http://creativecommons.org/licenses/by-nc/4.0 2023-07-21 2023-07-21 6 2 10.30953/bhty.v6.273 Blockchain in Healthcare: 2023 Predictions from Around the Globe https://blockchainhealthcaretoday.com/index.php/journal/article/view/245 <p>While the past 50 years have been categorized as the Information or Digital Age, the mass amounts of digitized data has been sorely underutilized. It was only recently through the COVID-19 pandemic that accelerated efforts were sought to harness this data with the use of blockchain technology in healthcare. Through the infrastructure and its tokenization applications, we can now effectively leverage healthcare data into more efficient business processes, secure better patient engagement and outcomes all while generating new revenue streams for an array of healthcare stakeholders. It is in compiling this stockpiled data into new, compliant business models and utilizing blockchain technology that we can reap the full potential of this era. Here are some predictions as to how we might set about these efforts in 2023.&nbsp;</p> Talisha Shine, MBA, CBE Jane Thomason, PhD, Msc. Imtiaz Khan, PhD Mohamed Maher, MBA Kohei Kurihara Copyright (c) 2023 Talisha Shine, MBA, CBE, Jane Thomason, PhD, Msc., Imtiaz Khan, PhD , Mohamed Maher, MBA , Kohei Kurihara http://creativecommons.org/licenses/by-nc/4.0 2023-01-31 2023-01-31 6 2 10.30953/bhty.v6.245 Moving Beyond Proof of Concept and Pilots to Mainstream: Discovery and Lessons from Blockchain in Healthcare https://blockchainhealthcaretoday.com/index.php/journal/article/view/280 <p>Blockchain technologies has been in the forefront of innovation and is maturing at a fast pace with fintech leading the way. Though the innovation in the permissionless space is high, the enterprise adoption has still not caught up. The reasons include a variety of reasons including inadequate understanding of the technology, full awareness even in enterprises, unclear regulations, and lack of exploration and evangelism to really understand the reimagination of shared enterprise business processes. Most enterprise blockchain efforts are run from a small exploratory group in large companies and has NOT moved beyond pilots or limited production tryouts in to mainstream adoption at scale. This is because there is not much knowledge about what is possible for reimagining current business processes which are mostly unilateral. This is more obvious in healthcare. A horizontal transformation enabler like the blockchain technology can effect collaborative business processes in a networked world. This paper explores the root causes for the challengesand suggests a methodology for discovery of the key inflection points for potential collaborative business processes and the re-engineering that would be needed. Blockchain in enterprise are not an isolated piece of technology, and has to interact with the enterprise assets, and there has to be mechanisms for aggregating the data that is meaningful to the counter parties for shared collaboration. Equally important is solid and a stair-stepping change management plan for the blockchain efforts to meet operations mainstream and gradually move the operations to the end state. Possibilities and results of the collaborative processes have to be shown in meticulous economic rigor for any possibilities of blockchain efforts getting the enterprise portfolio dollars against many enterprise systems that are already overloading budgets. The paper will cite the journey in a reference implementation with results, findings at the technical, functional, operational and change management levels for healthcare administration executives and portfolio managers.</p> Sathya Krishnasamy, MS Badri Narayanan Gopalakrishnan, PhD Copyright (c) 2023 Sathya Krishnasamy, MS http://creativecommons.org/licenses/by-nc/4.0 2023-12-29 2023-12-29 6 2 10.30953/bhty.v6.280 Impact of Blockchain-Digital Twin Technology on Precision Health, Pharmaceutical Industry, and Life Sciences Conv2X 2023 Report https://blockchainhealthcaretoday.com/index.php/journal/article/view/281 <p>The convergence of digital twin technologies with precision health, pharmaceutical industry, and life sciences has garnered substantial recent attention. As we advance toward personalized medicine and precision health, the fusion of digital twin and blockchain technologies is poised to fundamentally enhance healthcare outcomes. This conference discussion highlighted pivotal drivers accelerating the adoption of digital twin-enabled blockchain solutions, encompassing the shift to a decentralized world wide web (Web 3.0), the establishment of a global interconnected health ecosystem, and the distinct advantages offered by converging frontier technologies in optimizing healthcare, pharmaceutical industry, and life sciences. Yet, the effective deployment of blockchain-powered digital twins in precision health necessitates robust cyber safety measures, proactive ethical frameworks, data validation, provenance assurance, streamlined supply chain management, and heightened interoperability. The proceedings underscored Blockchain-powered Digital Twins' pivotal role in reshaping health data management, security, sharing, ownership, and monetization, as well as in revolutionizing pharmaceutical supply chain management and novel drugs and therapeutics development within the precision health domain.</p> Ingrid Vasiliu-Feltes MB EMBA Michael Mylrea, PhD Christina Yan Zhang, PhD Tyler Cohen Wood, CISSP Brian Thornley, BSc Copyright (c) 2023 Ingrid Vasiliu-Feltes MB EMBA, Michael Mylrea, PhD, Christina Yan Zhang, PhD, Tyler Cohen Wood, CISSP, Brian Thornley, BSc http://creativecommons.org/licenses/by-nc/4.0 2023-11-08 2023-11-08 6 2 10.30953/bhty.v6.281 S3EF-HBCAs: Secure and Sustainable Software Engineering Framework for Healthcare Blockchain Applications https://blockchainhealthcaretoday.com/index.php/journal/article/view/286 <p style="font-weight: 400;">Blockchain applications in healthcare have grown rapidly and it includes record keeping, clinical trials, medical supply chains, patient monitoring, etc. where Blockchain characteristics are needed to improve safety, privacy, and security. Blockchain Technology is one of the biggest disruptive technologies today. However, Porru, et. al (2017) have reported it lacks processes, tools, and techniques. Therefore, this paper provides a systematic framework for a secure and sustainable software engineering framework for healthcare blockchain applications. Secure and Sustainable Software Engineering Framework for Healthcare Blockchain Applications (S<sup>3</sup>EF-HBCA) significant contribution includes requirements engineering for healthcare, business process modelling for healthcare, domain modelling for healthcare, a reference architecture for healthcare, and validation by case study on Electronic Healthcare Record Management System (EHR), and simulation with Business Process Modelling Notation (BPMN) tools. The simulation shows it has taken 10.45 minutes to process 100 instances of real-time data and service requests. The overall result shows encouragement in terms of process, tools, standards, and testing.</p> Muthu Ramachandran, PhD Copyright (c) 2023 Muthu Ramachandran, PhD http://creativecommons.org/licenses/by-nc/4.0 2023-12-22 2023-12-22 6 2 10.30953/bhty.v6.286 Privacy-Conflict Resolution for Integrating Personal- and Electronic Health Records in Blockchain-Based Systems https://blockchainhealthcaretoday.com/index.php/journal/article/view/276 <p>Despite the great potential for healthcare professionals, individuals, and researchers, integrating healthcare information from personal health records (PHR) and electronic health records (EHR) systems is complicated because of structural- and semantic heterogeneity and -privacy. Healthcare data is an emotional issue because of fear of privacy violations. Blockchain technology enables a patient's data privacy, transparency, and immutability in cross-organizational processes where a patient regulates access to his data and is aware of its usage. At the same time, blockchain technology creates new challenges for e-healthcare systems, such as data privacy, observability, and online enforceability. In this paper, we propose a design and formalization of a secure blockchain-based, and patient-centric system with a definition of PHR requirements, an ontology for privacy-conflict resolution- and management mechanisms that takes into account the emotional aspects related to sharing sensitive healthcare records. Throughout this paper, we illustrate our ideas with a running case about preventive- and personalized healthcare.</p> Aleksandr Kormiltsyn, MSc Vimal Dwivedi, PhD Chibuzor Udokwu, PhD Alex Norta, PhD Sanam Nisar, MSc Copyright (c) 2023 Aleksandr Kormiltsyn, Vimal Dwivedi, Chibuzor Udokwu, Alex Norta http://creativecommons.org/licenses/by-nc/4.0 2023-12-15 2023-12-15 6 2 10.30953/bhty.v6.276 GAHBT: Genetic Based Hashing Algorithm for Managing and Validating Health Data Integrity in Blockchain Technology https://blockchainhealthcaretoday.com/index.php/journal/article/view/244 <p>This research work proposes a method for managing, securing, and validating the health data distribution records using a genetic-based hashing algorithm in a decentralized environment. The reason behind choosing blockchain is to secure the transaction of health data and protect the data from manipulated fraudulent movement and corruption by the contributor of the chain or any individual. The path of this technology approach provides an efficient surveillance measure such as transparency of record, fraud immunity, and protection to tempering and sustaining the order of data. In medical research, this paper provides a genetic-based hashing algorithm for data security which has lower computational complexity, low space coverage, higher security and integrity, and a high avalanche effect. The simulation will show data records' validity, immunity, and integrity. The technique modified in this secure decentralized network is a cryptographic hashing algorithm for 512 bits. In this study genetic algorithm is used to generate a key that needs to be used in the encryption and decryption of medical data. A genetic algorithm is a metaheuristic approach that is inspired by the laws of genetics and is generally used to generate high-quality solutions for complex problems. Applications of genetic algorithms encourage the significance in many medical fields such as radiology, oncology, cardiology, endocrinology, surgery, oncology, and radiotherapy in health care management.</p> Fozia Hanif Urooj Waheed Rehan Shams Aisha Shareef Copyright (c) 2023 Fozia Hanif, Urooj Waheed, Rehan Shams, Aisha Shareef http://creativecommons.org/licenses/by-nc/4.0 2023-02-07 2023-02-07 6 2 10.30953/bhty.v6.244 Why Industry-Wide Standards Matter In Fulfilling the Intent of DSCSA https://blockchainhealthcaretoday.com/index.php/journal/article/view/293 <p>Speakers discuss the importance of standardization in order to digitalize the U.S. pharmaceutical supply chain as motivated by the Drug Supply Chain Security Act (DSCSA).</p> <p>Key topics</p> <ul> <li>What is DSCSA?</li> <li>What does FDA’s Stabilization Period mean?</li> <li>Why do technology standards matter and how are they being implemented, i.e. interoperability through standards?</li> <li>Focus on standardization, due diligence in the context of DSCSA-regulated digitally managed pharma supply chain</li> <li>2023 readiness in relation to stabilization period until 2024</li> <li>Inspections will keep happening</li> <li>ATP is mandatory, authentication &amp; authorization</li> <li>Data security</li> </ul> Christiane Wirrig, PhD David Kessler Copyright (c) 2023 Christiane Wirrig, PhD, David Kessler http://creativecommons.org/licenses/by-nc/4.0 2023-12-03 2023-12-03 6 2 10.30953/bhty.v6.293